Heterogeneity appears to be as great in the cognitive domain as it is in the medical symptoms of the disorder Davenport et al. When patients are considered according to their age (≤3 years) and (>3 years), the older ones have more delayed development than the younger ones when compared with healthy individuals of the same age.ĬHARGE syndrome behavioral abnormalities cognitive impairment progress guide skills visual-auditory disabilities. However, since CHARGE syndrome appears to be a heterogeneous disorder from a cognitive point of view, the importance of individual differences should be emphasized. On the other hand, the expressive skills are still preserved. Historically, the diagnosis of CHARGE syndrome was based on the presence of specificclinical criteria. The condition has a variablephenotypic expression. Factors which correlate with better apparent development in the teen years include age of walking and degree of visual impairment. Abstract Background: CHARGE syndrome (CS) is a rare genetic condition (OMIM 214800). In particular, the delay is statistically significant in regard to self-care skills (worse toileting, better washing) and the communication skill (language). Although developmental delays might be expected in children with CHARGE syndrome, the incidence of cognitive impairment in CHARGE syndrome is probably 50 or less. Our main results show that Italian CHARGE patients have more delayed development in their physical abilities or skills with respect to normal patients. However, not much is known about language development in patients with CHARGE syndrome. Our purpose is to expand the knowledge of this syndrome by reviewing this group of affected patients in order to delineate in detail the natural history of the disease, and in particular to define the cognitive and motor profiles using an Italian questionnaire called "Progress Guide". 27145116 DOI: 10.1002/ajmg.a.37692 Abstract Hearing loss and cognitive delay are frequently occurring features in CHARGE syndrome that may contribute to impaired language development. Respiratory issues and complex cardiac defects often require early and frequent. CHARGE affects approximately 1 in every 9 to 10,000 live births, worldwide. Overview: CHARGE Syndrome is an extremely complex genetic condition encompassing anomalies of multiple systems. CHARGE syndrome is a multiple malformation syndrome involving ocular coloboma, heart defects, choanal atresia, retardation of growth and\or development, genital anomalies and\or urinary and ear abnormalities which leads to visual-auditory disabilities, cognitive impairment and behavioral abnormalities. Today’s guest post on genetic syndromes comes from Rebecca Freeh Thornburg, who is contributing on CHARGE Syndrome. Our investigation is the largest Italian cohort study of CHARGE patients. Since 2005, the Pediatric Clinic of Maternal-Infantile Sciences Institute in Ancona, in collaboration with the Lega del Filo d'Oro in Osimo, has been taking care of 35 patients with clinical and molecular diagnosis of CHARGE syndrome.
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''The Dalal street pounded amidst panic selling as the pandemic Covid-19 manifested itself in the minds of investors. Vinod Nair, head of research at Geojit Financial Services This will also affect the government’s fiscal maths, which was already tight.” At the same time Rising infections in India and associated disruption in businesses led to India’s GDP growth forecasts also being downgraded. "Indian markets ended at 3 year lows, with Nifty below the 8500 mark, in tandem with Asian and European markets after global agencies warned of a global recession following the impact of Covid-19. Kotak Mahindra Bank, Bajaj Finance and HDFC Bank shed 11.23 per cent, 11.11 per cent and 9.92 per cent respectively. IndusInd Bank tumbled 23.90 per cent as investors were worried about the lender’s exposure to Vodafone Idea to the tune of Rs 3,995 crore. They rose 9.83 per cent and 0.97 per cent, respectively.įinancials were the top losers. Only two Sensex stocks – ONGC and ITC-closed higher. BSE IT with a fall of 2.77 per cent was the least hit. Utilities, bankex and finance were among other sectors on the BSE that declined 7 per cent each. Vodafone Idea and Bharti Infratel nosedived 34.85 per cent and 22.62 per cent, respectively. It tumbled 9.48 per cent on the Supreme Court’s tough words. The market breadth was extremely bearish with more than five shares declining for every share that advanced on the BSE.īroader market was deep in the red as well, with BSE Midcap and BSE Smallcap indices declining 4.84 per cent and 6.09 per cent, respectively.Īll sectoral indices closed sharply lower with the BSE Telecom index hit the most. Banks have huge exposure to debt-laden telecom firms, and if telcos go bankrupt, it will result in higher NPAs for the banks. Following the scolding, the bears hammered bank and telecom shares. Here we shall choose the New Worksheet option. Otherwise, select the Existing Worksheet option and enter the target Location. The Create PivotTable window opens where we need to ensure the selected Table/Range is correct.Īnd if we want the pivot table in a new sheet, choose New Worksheet. Step 1: First, click on the table and select Insert > PivotTable to create a pivot table. Suppose we need to create a pivot chart in Excel for the below table. Let us understand the procedure using an example. Once formatted, we can make the best use of pivot chart in Excel by dynamically filtering and comparing the selected data series trends according to our requirements.Alternatively, we can click on the source data table and choose PivotChart à Pivot Chart & PivotTable to create the pivot table and chart together. Click on the table and select the PivotTable option in the Insert Then, click on the pivot table and choose the PivotChart option in the Insert tab.Ensure the source data is complete and accurate.The steps to create a pivot chart in Excel are: Thus, the pivot chart enables us to compare the sales generated by specific sales representatives or the chosen products, making it highly dynamic. The chart offers two filters, one for filtering products and the other for sales representatives. Later, we will see how to add a pivot chart to a new worksheet. In the pivot chart in Excel example, the graph gets plotted according to the pivot table in the cell range E1:I12, in the same sheet as the source data. Once we create a pivot table and insert pivot chart in Excel, the graph will appear as depicted below: Thus, the pivot chart is the best option users can use when summarizing, reviewing, or presenting massive data in sales and executive reports.įor example, consider the below table showing the sales data of sales representatives. It offers interactive filtering options that make analyzing the selected data quick and straightforward. In the PivotChart, click any interactive control, and then pick the sort or filtering options you want.Pivot chart in Excel is an in-built Excel feature that visually summarizes complex data and trends. If you don’t find a PivotChart you like, click PivotChart on the INSERT tab, instead of Recommended Charts. Once you find the PivotChart you like, click OK. A preview of your PivotChart appears in the preview pane. On the Recommended Charts tab, pick any chart with the PivotChart icon in the top corner. On the INSERT tab, in the Charts group, pick Recommended Charts. While a PivotChart shows data series, categories, and chart axes the same way a standard chart does, it also gives you interactive filtering controls right on the chart, so you can quickly analyze a subset of your data. In the Recommended PivotTables dialog box, click any PivotTable layout to get a preview, and then pick the one that shows the data the way you want, and click OK.Ī PivotChart can help you make sense of PivotTable data. Make sure your data has column headings or table headers, and that there are no blank rows.Ĭlick any cell in the range of cells or table. But sometimes it is hard to know where to start, especially when you have a lot of data.Įxcel can help you by recommending, and then, automatically creating PivotTables, which are a great way to summarize, analyze, explore, and present your data. Learn what a PivotTable and PivotCharts are, and how you can use them to summarize and analyze data in Excel 2013.Ĭreate a PivotTable to analyze worksheet dataīeing able to analyze all the data in your worksheet can help you make better business decisions. Reverting has two important advantages over resetting. In Git, this is actually called a reset, not a revert. It's important to understand that git revert undoes a single commit-it does not "revert" back to the previous state of a project by removing all subsequent commits. These are the other trees Git uses to manage the state of the repository. Instead of creating the new commit this option will add the inverse changes to the Staging Index and Working Directory. Passing this option will prevent git revert from creating a new commit that inverses the target commit. With the repo in this state, we are ready to initiate a git revert. At the end of the repo setup procedure, we invoke git log to display the commit history, showing a total of 3 commits. We have made 3 commits to the repo in which we have added a file demo_file and modified its content twice. Here we have initialized a repo in a newly created directory named git_revert_test. Initialized empty Git repository in /git_revert_test/.git/ $ touch demo_file $ git add demo_file $ git commit -am"initial commit" initial commit 1 file changed, 0 insertions(+), 0 deletions(-) create mode 100644 demo_file $ echo "initial content" > demo_file $ git commit -am"add new content to demo file" add new content to demo file n 1 file changed, 1 insertion(+) $ echo "prepended line content" > demo_file $ git commit -am"prepend content to demo file" prepend content to demo file 1 file changed, 1 insertion(+) $ git log -oneline 86bb32e prepend content to demo file 3602d88 add new content to demo file 299b15f initial commit $ mkdir git_revert_test $ cd git_revert_test/ $ git init . To demonstrate let’s create an example repo using the command line examples below: The ref pointers are then updated to point at the new revert commit making it the tip of the branch. A revert operation will take the specified commit, inverse the changes from that commit, and create a new "revert commit". Git revert also takes a specified commit, however, git revert does not move ref pointers to this commit. Other 'undo' commands like, git checkout and git reset, move the HEAD and branch ref pointers to a specified commit. The git revert command is used for undoing changes to a repository's commit history. Instead of manually going in, fixing it, and committing a new snapshot, you can use git revert to automatically do all of this for you. This can be useful, for example, if you’re tracking down a bug and find that it was introduced by a single commit. Reverting should be used when you want to apply the inverse of a commit from your project history. This prevents Git from losing history, which is important for the integrity of your revision history and for reliable collaboration. Instead of removing the commit from the project history, it figures out how to invert the changes introduced by the commit and appends a new commit with the resulting inverse content. The git revert command can be considered an 'undo' type command, however, it is not a traditional undo operation. The table below summarizes the features to help you choose. The best Outlook email encryption option for you among the available ones depends on the ease of use for you and your recipients, available features such as access to encrypted messages outside Outlook, costs, and other capabilities. Also, this is likely the lowest cost option, or even free. So this option to encrypt email in Outlook combines the best of both the previous two options. Using Email Encryption Add-ins: The right Outlook email encryption add-in can let you send encrypted to any recipient (any email address, including free webmail users) using any email account.This option is also likely the most expensive. Also, you need the Outlook application installed as part of the Office 365 subscription (this encryption option is not available in Outlook 2013, Outlook 2016, or Microsoft Office one time license purchases). However, this option is only available to you if you use an Office 365 email account (Exchange Online). Office 365 Message Encryption (OME): This option does not require installing certificates and allows you to send encrypted messages to any email recipient.This option is not available for you if you need to send encrypted email to free webmail users such as clients on Gmail, Yahoo, iCloud etc. Both you and your email recipients must also install and share encryption certificates. Using digital IDs (certificates) for sender and recipients (S/Mime): This option works with any email account that you have added to Outlook but requires your recipients to also use Outlook (or an S/Mime compatible email application).The three options and their availability scenarios are: Which of the three Outlook email encryption options are available to you depends on who your recipient is and which email account you are using to send encrypted email. Questions: Which email encryption options are available in your scenario and which one should you choose? How do you set up your selected encryption option and get started sending and receiving secure email? How do you obtain encryption certificates for Outlook, for yourself and your recipients? Which option gives you the Outlook Encrypt button? Did you know that the Microsoft Outlook desktop application offers three methods to encrypt emails, including the latest OME option that does not require installing certificates and lets you send encrypted email to external recipients (such as free web mail users on Gmail, Yahoo! Mail, or any other email account)? Jeff had an elaborate vintage analog delay in a rack, and that thing was lush one of the warmest delays I’ve heard. We did the standard quick harp setup: reduce the gain, roll off the treble and boost the bass. The Two-Rock J-2 is a 40-watt amp with two 6L6 power tubes. I’ve never heard anything quite like it in one amp before. It is a combination of my Mission 5F2H (great crunch) and my Masco ME-18 (beautiful wamth) and a Victoria 5112 (gorgeous texture and dynamics) and a big old Tweed Pro (savage bark). The amp is warm and smooth and fat as hell, but also crunchy and responsive to pressure from the mic. There are good reasons why this amp costs four grand. I didn’t have my Zoom H4 recorder, but I’ll take it next week and try to get some sound clips. He was unendingly generous with his amp and advice. But I had my eye on that Two-Rock and asked Jeff at the break if I could plug in and try it out. The tone was excellent and I enjoyed playing through it. I want one.ĭuring my set I plugged into a Blackface Fender Deluxe Reverb (not a re-issue) that had been modified with beefier trannies from a Bassman. Jeff was the nicest, most unpretentious guy on earth and a very talented guitar player, and his amp kills. Jeff brought a Two-Rock J-2 10th Anniversary Edition amp to the jam… a $4000 amp about the size of a Fender Pro Junior. Last night at the Wednesday blues jam at Bushwacker’s in Denver I got schooled about that. For years I have suffered under the notion that guitar players who drag elite boutique (read: hyper-expensive) amps to blues jams are pretentious twits with more money than talent. You can also use the grep command to search for targets that are defined as patterns by using regular expressions. The following example shows how to search through all the files in the current directory for lines that do not contain the letter e. To search for all the lines of a file that do not contain a certain string, use the -v option to grep. Searching for Lines Without a Certain String When it finds a pattern that matches in more than one file, it prints the name of the file, followed by a colon, then the line matching the pattern.Īlaska:Alaska is the largest state in the United States. The grep command can search for a string in groups of files. To find a pattern that is more than one word long, enclose the string with single or double quotation marks. The search provides the following results. The second part of the command line pipes that list through grep, looking for the pattern Sep. The first part of this command line produces a list of files ending in. ps” and were created in the month of September. The following example displays files that end in “. To use grep as a filter, you must pipe the output of the command through grep. You can use the grep command as a filter with other commands, enabling you to filter out unnecessary information from the command output. Note that grep failed in the first try because none of the entries began with a lowercase a. Grep is case sensitive that is, you must match the pattern with respect to uppercase and lowercase letters: Note that more than one line might match the pattern you give. $ grep Poe extensions Edgar Allan Poe x72836 Strings can include blank spaces, punctuation, and invisible (control) characters.įor example, to find Edgar Allan Poe's telephone extension, type grep, all or part of his name, and the file containing the information: A single letter is a string, as is a word or a sentence. In this example, string is the word or phrase you want to find, and file is the file to be searched.Ī string is one or more characters. To search for a particular character string in a file, use the grep command. amid speculation about a budding romance with football great Tom Brady Kim Kardashian showcases her toned abs in a bikini top. Salma Hayek, 56, flaunts her incredible curves in a skimpy bikini in VERY racy video as she thanks her 25 million Instagram followers Look away Bad Bunny! Kendall Jenner dances the night away with $180M French footballer Kylian Mbappé at star-studded party in the Hamptons Amazon pulls listings for 'steering wheel weights' that allow Tesla drivers to trick the vehicle into thinking their hands are on the wheel while on self-driving mode.White House defends sending cluster munitions to Ukraine: Biden's National Security Advisor says Russia is ALREADY using them and Kyiv has given 'assurances' they'll minimize risk to civilians - after previously claiming it would start World War Three.The Grass Ceiling: Gardeners' World star Carol Klein blasts show's lack of female representation.New crackdown on anti-social behaviour will see fines for graffiti and littering rise more than threefold to £500.'I thought, he's a man!': Zoe Ball leaves son Woody, 22, CRINGING on Celebrity Gogglebox after she proudly recalls finding his USED condom.Neo-Nazi podcasters who said Prince Harry and Meghan's son Archie is an 'abomination that should be put down' for being mixed race are convicted of terror crimes.New video shows moment Britney Spears was smacked by NBA star Victor Wembanyama's security guard after chasing after him and yelling 'sir' in a British accent.It was game on with Tom Brady and model Emily Ratajkowski - NOT Kim Kardashian - at Michael Rubin's star-studded Fourth of July bash as insiders claim they were 'together most of the night'.Ethical vegans should NOT have kids if they truly believe 'unnecessary suffering' should be avoided, ethicist controversially claims.
This means that when playing – you will need to select 6 numbers out of a range of numbers from 1 to 45. The Australian Superdaw – TattsLotto Superdraw – operates in exactly the same manner as the weekly Saturday Lotto using a 6/45 NSW Lotteries have many games in their lottery portfolio including the Oz Lotto, Lotto Strike, Saturday Lotto, Wednesday Lotto, Monday Lotto, Instant Scratchies, the Powerball Australia, the Australian Pools, the Lucky Lotteries games which comprise of the Super Jackpot Lottery and the Mega Jackpot Lottery plus the TattsLotto Suprdraw which we are going to look at further here. Since its beginning over 80 years ago – NSW Lotteries have raised billions of dollars for the NSW government that have helped to fund a range of services for New South Wales citizens.Įach year nearly 1/3 of the money that is spent on NSW Lottery games is returned directly to the government and more than 60% of money spent is put straight back into its own lottery prize pool – one of the highest returns among lottery games around the world. Games across both New South Wales and the Australian Capital Territory. They are fully licensed to conduct various Australia Lotto Have been around since 1931 and are owned by the government of New South Wales and leased by Tatts. Games alongside the TattsLotto, Oz Lotto, Powerball Australia as well as the Monday Lotto and Wednesday Lotto. – are a leading operator of Australian Lottery games and are part of theĪustralian Lotto Bloc that collectively offer the Australian Superdraw New South Wales Lotteries – NSW Lotteries Of entry are the same as the weekly equivalent – Saturday Lotto. The jackpots are generally higher but the odds of winning and the cost Too than the regular weekly Australian Lottery games – this is due to the fact that The Superdraw offers better value for money The TattsLotto Superdraw pays out some of the biggest jackpots and provides the best odds of winning the lottery than almost all of the other lottery games offered in the Asia/Pacific region. The Megadraw jackpot is usually around the AUS$ 30 MILLION mark and has been known to reach as high as AUS$ 32 MILLION. The Australian MEGADRAW – which has even bigger jackpots than the Superdraw and is generally held once a year in January. Ĭomplimenting the TattsLotto Superdraw is another huge drawing – TattsLotto Superdraw jackpot prizes range from a huge AUS$ 20 MILLION to a truly staggering AUS$ 30 MILLION. Members of the Australian Lotto Bloc – which includes Tatts, NSW Lotteries, Golden Casket, Lotterywest and SA Lotteries – pool a portion of the revenue from their weekly Australia Lotto games to fund these special TattsLotto Superdraw occasions. – usually at special dates in the Australian calendar such asĪustralian public holidays or around Christmas and New Year. The TattsLotto Superdraw game typically occurs 7 or 8 times per year The standard weekly games of Australian Lotto including the countrywide Oz Lotto and the popular Powerball Australia. – or the TattsLotto Superdraw – offers bigger jackpots to be won than all of I really pushed myself to the max on day eight and burned 293 Calories. My abs were looking SHREDDED and I was so so happy that I was making progress. I really started to see some big results on this day. All in all I pushed myself and got in another great workout, burning 279 Calories.Īriana Grande Abs Day Eight- Starting Physiqueĭay Eight was amazing. Once again, the workouts didn’t seem as taxing, although I still hated every second I spent doing Up and Down Plank. I ended up burning 334 Calories on this day.ĭay Seven was a tough one, but I really pushed myself and could tell that I’d been making progress. I also really started to notice my stomach getting more toned and I believe this helped motivate me to push myself harder due to the results I was seeing. I could definitely tell that my endurance for the workout program was getting stronger, as I didn’t feel as exhausted when I finished the daily routine. Lower Body Burn Day Six- Starting Physiqueĭay Six was back to the grind. I ended off my session by using my resistance bands to do a Chloé Ting Booty workout that was killer and amazing, I burned 409 Calories and really felt great doing so. I took the liberty to run on the elliptical and then do some core and back workouts by Chloe Ting. I don’t think I’ve ever been happier to not have to do an Up and Down Plank. It was also on this day that I began to find the hardest exercise to be In and Out Squats during the “Do This Everyday to Lose Weight” video.Īctive Rest Day Day Five- Starting Physiqueĭay Five was an active rest day. I began to seethe with resentment towards the Up and Down Planks, but I still pushed myself to the limits and burned 368 Calories. This was my first time having to do 5 Up and Down Planks in one session and I was not feeling it. Tight Core and Arms Workout Day Four- Starting Physiqueĭay Four had me DYING. Still, I pushed and gave it my all and ended up burning 328 Calories. The leg workout just about killed me and I was starting to get sick of the Up and Down Planks. Still, I pushed myself really hard and got in a great workout, buring 320 Calories total.ĭay Three I was really feeling the burn. I definitely was feeling the burn from day one and found the second day to be more difficult than the first day. I got in a great sweat and ended up burning 324 Calories in the 23 minute workout.ĭay Two I thought was going to be easier than the first day… I was mistaken. There were two workouts for the first day and while both were quite challenging, I pushed myself to do the very best I could. I was so excited to get this challenge started! I had buckets of energy. I am pleased to say that while I did suffer immense pain, I plan to try her 2020 Shred Challenge in the month of June.Ģ Weeks Abs Workout Challenge Day One- Starting Physiqueĭay one I was feeling great. Overall, this challenge wasn’t about losing weight or getting abs, it was about pushing myself to new limits and doing they very best I could each and everyday. However, this was my first time following one of her free programs day by day and step by step. I also have attempted some of her other HIIT workouts, along with her Booty and Arm workouts too. When I started my fitness journey back in August of 2018, I found Chloe Ting on YouTube and began to incorporate her Ab workouts into my own daily fitness routine. Now, I didn’t just jump on the #chloetingchallenge train, I’ve been a longtime STAN of Chloe Ting for almost two years. Attempting this challenge together was a great way to encourage and motivate each other to keep going, and we were able to bond over our new seething resentment towards the infamous “Up and Down Plank.” Naturally, if I was going to suffer so would my parents. With a lack of structure comes boredom, so since the beginning of May I have been working hard to complete Chloe Tings Two Week Shred Challenge on YouTube. With quarantine still underway and the weather being cold and dreary, my cabin fever has been through the roof since the end of the school year. Hello friends, and welcome to another Workout Wednesday. |
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